A new study from the large-scale DO-HEALTH clinical trial has revealed that a daily combination of omega-3 supplements, vitamin D and regular exercise may modestly slow biological aging in older adults.
Published in Nature Aging, the study followed 777 healthy participants aged 70 and above over a span of three years. Researchers used four DNA methylation-based epigenetic clocks including PhenoAge, GrimAge, GrimAge2 and DunedinPACE, to measure biological aging.
The findings showed that participants who took 1 gram of omega-3 fatty acids daily experienced a reduction in biological aging by approximately 2.9 to 3.8 months. When this was combined with 2,000 IU of vitamin D and a simple home-based strength and balance exercise routine performed three times weekly, the benefits appeared more significant.
Lead author Dr. Heike Bischoff-Ferrari stated, “Our findings provide a strong signal that omega-3 supplementation slows biological aging in humans and that the combination with vitamin D and exercise may enhance this effect.”
Though the reduction in biological age may seem modest, experts suggest that even slight delays in the aging process could have meaningful impacts on long-term health, especially in reducing the burden of age-related diseases.
The study highlights the growing interest in low-cost, accessible interventions for promoting healthy aging, though more research is needed to determine long-term outcomes across diverse populations.
Disclaimer: This article is for informational purposes only and is not intended as medical advice. Always consult your healthcare provider before starting any new supplement or exercise routine, especially if you have underlying health conditions or are taking medications.
